MANFREDI Marcello
Research Activity
Brief Research Description
The research activity is divided into the following research lines:
1- Multi-omics approaches for biochemical phenotyping: proteomics, metabolomics and lipidomics analyses of cell lines, tissues and biological fluids, data integration (cancer, autoimmune diseases, neurodegenerative diseases and aging)
2- Biomarkers and therapeutic targets discovery: Proteomics and metabolomics to discover new biomarkers, biomarker validation with ELISAs.
3- Multivariate analysis, data integration, artificial intelligence: multivariate analysis, integration of metagenomic, metaproteomic and metabolomic data, system biology and modelling.
4- In vitro and in vivo studies: Study of the effect of natural substances on cancer cell lines, effect of probiotics on heath and pathologies, studies on mouse models of human diseases.
5- Development of diagnostic kits and tests.
Keywords
Biochemistry; multi-omics; biomarkers and therapeutic targets; health and diseases; aging