ESPINOZA Stefano

Research Activity

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Brief Research Description

The main aim of my research is to harness the potential of SINEUPs as a novel tool in gene therapy for neurological disorders. 

During my career, I have been always interested in neurological and neuropsychiatric disorders, especially those linked to dysfunctions of the dopamine system. After working for three years in a pharmaceutical company developing antipsychotic compounds, I continued to work as a neuropharmacologist in characterizing the physiology of a new class of GPCRs, namely trace amine-associated receptors, and to understand their role in several brain diseases. 

In the last few years, I focused my research on the potential use of SINEUPs as a novel treatment for Parkinson’s disease and other neurological disorders. Currently, I’m actively working on projects to develop SINEUPs for different neurodevelopmental disorders.

(Scopus unique identifier 36339051000)


Keywords

Neuroscience, pharmacology, RNA therapeutics, gene therapy, neurologic disorders 


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